Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interocular transfer in cats with early callosal transection.

M Ptito, F Lepore

    Nature
    |February 10, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Uncovering a Role for the Dorsal Hippocampal Commissure in Recognition Memory.

    Cerebral cortex (New York, N.Y. : 1991)·2019
    Same author

    Two-stage reimplantation in periprosthetic knee infection.

    European review for medical and pharmacological sciences·2019
    Same author

    Distribution and Morphology of Cortical Terminals in the Cat Thalamus from the Anterior Ectosylvian Sulcus.

    Scientific reports·2019
    Same author

    Uncertainty about the intensity of impending pain increases ensuing pain responses in congenital blindness.

    Behavioural brain research·2017
    Same author

    Impact of video games on plasticity of the hippocampus.

    Molecular psychiatry·2017
    Same author

    Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness.

    Neural plasticity·2017

    The visual system

    Area of Science:

    • Neuroscience
    • Developmental Neuroscience
    • Visual System Plasticity

    Background:

    • The visual system exhibits plasticity, especially during early life critical periods.
    • The corpus callosum, a major interhemispheric pathway, is crucial for visual information transfer.
    • Previous research suggests potential plasticity in the commissural system.

    Purpose of the Study:

    • To investigate the functional plasticity of the secondary commissural system.
    • To determine the critical period for plasticity in the corpus callosum's visual pathways.
    • To assess interhemispheric transfer of visual information after early callosal interventions.

    Main Methods:

    • Sectioning of the corpus callosum in kittens at different developmental stages (pre- and post-maturation).

    Related Experiment Videos

  • Subsequent optic chiasm transection in adulthood.
  • Comparison of interhemispheric transfer of monocularly learned pattern discriminations in split-brain cats.

    • Main Results:

    • Kittens with early callosal sectioning (before maturation) showed significant interhemispheric transfer.
    • Animals with later callosal sectioning did not demonstrate significant transfer.
    • This indicates functional plasticity in the secondary commissural system with a brief critical period.

    Conclusions:

    • The secondary commissural system demonstrates functional plasticity.
    • The critical period for this plasticity is very short and may precede optimal callosal pathway activation.
    • Early intervention is key for visual system reorganization in the commissural pathway.