Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascular changes in rhegmatogenous retinal detachment.

F Cardillo Piccolino

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1983
    PubMed
    Summary

    This study reveals that capillary changes in rhegmatogenous retinal detachment are an autoregulation response to hypoxia. Peripheral vascular occlusions indicate pre-existing perfusion issues exacerbated by detachment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Transpupillary thermotherapy of juxtafoveal recurrent choroidal neovascularization.

    European journal of ophthalmology·2003
    Same author

    Grid laser treatment of occult choroidal neovascularization in age related macular degeneration.

    International ophthalmology·1993
    Same author

    Fundus angiography with fluorescein-labelled peptide fraction from bovine factor VIII: correlation with histologic findings.

    European journal of ophthalmology·1992
    Same author

    Pattern dystrophy of the retinal pigment epithelium with vitelliform macular lesion: evolution in ten years.

    International ophthalmology·1988
    Same author

    Classification of proliferative diabetic retinopathy.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·1987
    Same author

    Mesectodermal leiomyoma of the ciliary body extending into the anterior chamber.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·1985

    Area of Science:

    • Ophthalmology
    • Retinal Vascular Diseases
    • Medical Imaging

    Background:

    • Rhegmatogenous retinal detachment (RRD) is a significant cause of vision loss.
    • Understanding the vascular dynamics in RRD is crucial for effective treatment.
    • Previous studies have suggested but not fully elucidated the role of vascular changes in RRD pathogenesis.

    Purpose of the Study:

    • To investigate the vascular conditions in patients with rhegmatogenous retinal detachment using fluorescein angiography.
    • To explore the relationship between retinal detachment, hypoxia, and vascular changes.
    • To identify typical vascular findings associated with peripheral holes in RRD.

    Main Methods:

    • Fluorescein angiography was performed on 50 patients diagnosed with rhegmatogenous retinal detachment.
    • Vascular changes in the detached retina were systematically analyzed.
    • Correlation between the location of retinal holes and vascular occlusion patterns was examined.

    Main Results:

    • Capillary dilatation and hyperpermeability were observed in the detached retina, suggesting an autoregulation mechanism.
    • These vascular changes are likely secondary to tissular hypoxia.
    • Diffuse peripheral vascular occlusions were common in detachments with peripheral holes.
    • Preexisting retinal perfusion defects may be worsened by increased resistance caused by the detachment.

    Conclusions:

    • Vascular alterations in RRD, including capillary changes and peripheral occlusions, are linked to hypoxia and pre-existing perfusion defects.
    • Fluorescein angiography is a valuable tool for assessing these vascular dynamics in RRD.
    • Findings highlight the complex interplay between retinal detachment, vascular health, and visual prognosis.

    Related Experiment Videos