Characterization of ornithine decarboxylase activity in human uterine decidua vera

Ornithine decarboxylase (ODC) catalyzes the rate-limiting step in the biosynthesis of the polyamines putrescine, spermidine, and spermine. In the present study, we characterized the activity of ODC in human uterine decidua vera tissue. We evaluated the activity of the enzyme in decidua vera tissue that was obtained from pregnancies at term before or after the spontaneous onset of labor and in decidua vera tissue that was obtained between 8 and 18 weeks' postconceptional gestational age at the time of elective abortion. Among these tissues, no significant differences in ODC activity were demonstrable.