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Updated: Aug 9, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
[Heart operations on young children under deep hypothermia]
Insights
Deep hypothermia with extracorporeal circulation is a viable treatment for pediatric heart defects, showing promising low mortality rates, especially for ventricular septal defects. Long-term follow-up indicates no adverse effects on the central nervous system.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Hypothermia Therapy
Context:
- Clinical application of deep hypothermia and extracorporeal circulation in pediatric cardiac surgery.
- Evaluation of surgical outcomes and patient survival rates in a cohort of 124 children.
Purpose:
- To assess the efficacy and safety of deep hypothermia combined with extracorporeal circulation in pediatric patients undergoing cardiac repair.
- To analyze mortality rates associated with different cardiac defect corrections and evaluate long-term neurological outcomes.
Summary:
- The study involved 124 pediatric patients undergoing cardiac surgery using deep hypothermia and extracorporeal circulation, reporting an overall mortality of 23.4%.
- Correction of ventricular septal defects showed the lowest mortality, with 14.6% (12 out of 82 patients).
- Remote follow-up assessments confirmed no detrimental impact of the procedure on the central nervous system.
Impact:
- Provides critical data on the outcomes of deep hypothermia in pediatric cardiac surgery.
- Highlights the safety and effectiveness of this combined approach for specific congenital heart defects.
- Offers reassurance regarding the neurological integrity of pediatric patients post-procedure, supporting its continued clinical use.
Abstract:
The authors discuss their clinical experience in the use of deep hypothermia in combination with auxiliary extracorporeal circulation. Operations were performed on 124 children (total mortality 23.4%). Lowest mortality was noted in correction of ventricular septal defect; 12 out of 82 patients died, which accounts for approximately 14.6%. A follow-up of the remote results shows that the method has no harmful effect on the central nervous system.
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