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Arthritis in Behcet's syndrome.

N Caporn, E R Higgs, P A Dieppe

    The British Journal of Radiology
    |February 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Behcet's syndrome frequently causes joint pain, including peripheral arthritis and low back pain with sacro-iliitis. Radiographic findings are often absent in peripheral joints but can show sacro-iliitis in Behcet's patients.

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    Area of Science:

    • Rheumatology
    • Immunology
    • Radiology

    Background:

    • Behcet's syndrome is a multisystem inflammatory disorder.
    • Joint disease is a common manifestation of Behcet's syndrome.
    • Radiological features of joint involvement in Behcet's syndrome require further elucidation.

    Purpose of the Study:

    • To review the clinical and radiological features of joint disease in patients with Behcet's syndrome.
    • To assess the prevalence of peripheral arthritis, sacro-iliitis, and enthesopathy.
    • To determine the association between sacro-iliitis and HLA B27 antigen in these patients.

    Main Methods:

    • Retrospective review of clinical and radiological data from fourteen patients diagnosed with Behcet's syndrome.
    • Clinical assessment of joint pain, including peripheral oligo- or poly-arthritis and low back pain.

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  • Radiological evaluation focusing on peripheral joints, sacroiliac joints, and spine for abnormalities like erosions and vertebral squaring.

    • Main Results:

    • Thirteen out of fourteen patients (93%) experienced recurrent peripheral oligo- or poly-arthritis.
    • No radiographic abnormalities were observed in the peripheral joints.
    • Ten patients (71%) reported low back pain, with seven (50%) showing mild erosive sacro-iliitis.
    • Five patients (36%) had enthesopathy, including calcaneal spurs, and one also had vertebral body squaring.
    • Patients with sacro-iliitis were negative for the HLA B27 antigen.

    Conclusions:

    • Peripheral arthritis is a highly prevalent feature of Behcet's syndrome, often without peripheral joint radiographic changes.
    • Sacro-iliitis is a significant radiological finding in Behcet's syndrome, occurring independently of the HLA B27 antigen.
    • Behcet's syndrome should be considered in the differential diagnosis of sacro-iliitis presenting with clinical arthropathy.