Related Experiment Video
Updated: Aug 12, 2026

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
Published on: March 11, 2017
Recurrence of intravenous-diazepam-induced phlebitis from oral diazepam
Abstract:
A patient who developed phlebitis from the intravenous administration of diazepam is described. This episode resolved in two days after treatment with moist heat packs. Three days after complete resolution, the phlebitis recurred approximately eight hours after a single oral dose of diazepam. This recurrence of phlebitis resolved slowly over seven days, with warm soaking and aspirin therapy. Oral diazepam may have exacerbated the initial phlebitis by interfering with a subclinical healing process.
Insights
Phlebitis, an inflammation of a vein, recurred in a patient after oral diazepam administration, even after initial intravenous treatment resolved. This suggests oral diazepam may impede vein healing processes.
Area of Science:
- Pharmacology
- Vascular Medicine
Background:
- Phlebitis is a common complication of intravenous drug administration.
- Diazepam is a widely used benzodiazepine medication.
Related Concept Videos
Parenteral Anesthetics: Overview
Drug Accumulation During Multiple Dosing: Repetitive IV Injections
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
IV Infusion to Oral Dosing: Conversion Methods
Venous Thrombosis III: Interprofessional Care
Pulmonary Embolism III: Nursing Management

