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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...

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Related Experiment Video

Updated: Jul 1, 2026

In vitro Functional Characterization of Mouse Colorectal Afferent Endings
14:09

In vitro Functional Characterization of Mouse Colorectal Afferent Endings

Published on: January 21, 2015

Colonic electromyography in chronic constipation.

G Frieri, F Parisi, E Corazziari

    Gastroenterology
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Chronic constipation in patients is linked to an increased frequency of slow colonic rhythms in the sigmoid. This heightened electrical activity may cause more contractions, slowing intestinal transit.

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    In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats
    08:19

    In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats

    Published on: September 27, 2017

    Area of Science:

    • Gastroenterology
    • Physiology

    Background:

    • Chronic constipation affects a significant portion of the population.
    • Understanding the underlying mechanisms of colonic dysfunction is crucial for effective treatment.

    Purpose of the Study:

    • To investigate the myoelectric activity of the sigmoid colon in patients with chronic nonorganic constipation.
    • To compare colonic electrical and mechanical activity between constipated patients and healthy controls.

    Main Methods:

    • Intraluminal recording of electrical and mechanical activity using a probe with bipolar suction electrodes.
    • Analysis of slow wave frequencies (approx. 3 and 6 cycles/min) and motility index.
    • Assessment of total gastrointestinal transit time.

    Main Results:

    • Patients with chronic constipation exhibited significantly higher frequencies of the slower colonic rhythm (approx. 3 cycles/min) in the sigmoid compared to controls.
    • No significant differences were observed in the faster rhythm frequency or incidence between groups.
    • Mechanical activity, measured by motility index, did not differ between constipated patients and controls.

    Conclusions:

    • An increased frequency of the slower sigmoid rhythm is associated with left colonic constipation.
    • This heightened slow-wave activity may lead to increased segmenting contractions, contributing to slowed intestinal transit.
    • The findings suggest a potential role for abnormal electrical activity in the pathophysiology of chronic constipation.