Related Experiment Videos
Abstract:
Somatic cell hybrids between rodent cells and owl monkey cells preferentially segregating primate chromosomes were selected for mapping owl monkey genes. Concordant segregation of phenotype and chromosome in 35 independent hybrid clones and 105 subclones with different reduced owl monkey complements provided evidence for the assignment of 17 gene loci to 9 chromosomes of the Bolivian owl monkey with a karyotype VI (2n = 49 male, 50 female). The assignments include: MDH1 to chromosome 2, MDH2 to chromosome 4, FH to chromosome 6, LDHB to chromosome 10, NP-MPI-PKM2-SORD to chromosome 11, PGM1-PGD-AK2-ENO1 to chromosome 12, LDHA to chromosome 19, GPI to chromosome 25 and PGK-G6PD-GLA to the X chromosome.