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Regulation of the macrophage content of neoplasms by chemoattractants
Science (New York, N.Y.)
|April 8, 1983
Abstract:
Factor chemotactic for mononuclear phagocytes was found in supernatant fluids of cultured human and mouse tumor cells. In 11 mouse tumors there was a correlation observed between chemotactic activity and macrophage content of neoplastic tissues. Tumor-derived chemoattractants appear to participate in the regulation of tumor-associated macrophages.