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Magnesium--distribution and basic metabolism.

J V Olhaberry, W P Leary, A J Reyes

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |February 26, 1983
    PubMed
    Summary
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    Magnesium is vital for enzymatic reactions and human health, with most bodily stores found in bone and intracellularly. Dietary intake recommendations are established for maintaining adequate magnesium levels.

    Area of Science:

    • Biochemistry
    • Human Physiology
    • Nutritional Science

    Background:

    • Magnesium is a ubiquitous element found in soil, water, and plants.
    • It plays a crucial role in enzymatic reactions dependent on adenosine triphosphate (ATP).
    • The human body stores approximately 50% of its magnesium in bone.

    Purpose of the Study:

    • To outline the distribution and physiological importance of magnesium in the human body.
    • To detail the recommended dietary allowance for magnesium.
    • To describe the regulation of bone magnesium storage.

    Main Methods:

    • Literature review on magnesium's biological roles and distribution.
    • Analysis of established dietary guidelines for magnesium intake.
    • Examination of hormonal regulation of magnesium homeostasis.

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    Main Results:

    • Magnesium is essential for numerous enzymatic processes.
    • The recommended daily intake for humans is 5-10 mg/kg/d.
    • Bone and intracellular compartments house the majority of the body's magnesium, with plasma levels being minimal.

    Conclusions:

    • Magnesium is a critical mineral with widespread physiological functions.
    • Bone and intracellular magnesium are tightly regulated.
    • Maintaining adequate dietary intake is essential for overall health.