[Polyamine contents in the brain and liver of rats during acclimatization to the cold]

The content of polyamines, spermidine and spermine in the brain and liver was studied in rats during acclimation to cold for 45 days. In the brain the amount of spermidine after one and three days does not change, on the 7th and 15th day it decreases and by the end of acclimation returns to the control value. The content of spermine lowers by 29% by the third day of acclimation and on the 7th day returns to the initial level and does not change up to it end. In the liver the amount of spermidine rises significantly on the third day of acclimation, returns to the control level on the 7th day and then its amount falls. The content of spermine is increased in all period of acclimation and only by the 45th day it returns to its initial level.