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Continuous ambulatory peritoneal dialysis in a pediatric population
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Continuous ambulatory peritoneal dialysis (CAPD) effectively managed uremia in children with end-stage renal disease. This study highlights CAPD as a viable long-term alternative to hemodialysis, showing good growth and psychosocial adjustment.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Peritoneal Dialysis
Background:
- End-stage renal disease (ESRD) in children presents significant therapeutic challenges.
- Long-term dialysis options for pediatric ESRD require careful consideration of growth and psychosocial factors.
- Continuous ambulatory peritoneal dialysis (CAPD) offers a potential home-based treatment modality.
Purpose of the Study:
- To evaluate the efficacy and safety of CAPD in pediatric patients with ESRD.
- To assess growth rates and psychosocial adjustment in children undergoing CAPD.
- To compare CAPD as a long-term therapy alternative to hemodialysis.
Main Methods:
- Retrospective analysis of seven pediatric patients (6 weeks to 14 years) treated with CAPD.
- Study duration of 60 patient-months.
- Monitoring of uremic control, peritonitis incidence, growth parameters, and psychosocial well-being.
Main Results:
- Satisfactory control of uremia was achieved in all patients.
- Seven episodes of peritonitis occurred (1 per 8.6 patient-months) without compromising dialysis efficacy or membrane permeability.
- Patients over 5 years showed growth comparable to hemodialysis patients; infants exhibited normal growth rates. Families reported good psychosocial adjustment.
Conclusions:
- CAPD is an effective and safe treatment for pediatric end-stage renal disease.
- CAPD supports adequate growth and positive psychosocial adaptation in children.
- Continuous ambulatory peritoneal dialysis is a satisfactory long-term alternative to hemodialysis for pediatric ESRD management.
Abstract:
Seven children aged from 6 weeks to 14 years were treated for end-stage renal disease by continuous ambulatory peritoneal dialysis (CAPD) for 60 patient months. Satisfactory control of their uremia was achieved. Peritonitis was diagnosed on seven occasions (one case per 8.6 patient months) and did not interfere with continuation of dialysis or decrease peritoneal membrane permeability. Patients older than 5 years grew at rates comparable with those of patients receiving hemodialysis. Two infants receiving CAPD exhibited normal growth rates. Families demonstrated good psychosocial adjustment to the technique. Thus, CAPD seems to be a satisfactory alternative to hemodialysis for long-term therapy .