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Related Experiment Videos

Streptococcus milleri and surgical sepsis.

J C Tresadern, R J Farrand, M H Irving

    Annals of the Royal College of Surgeons of England
    |March 1, 1983
    PubMed
    Summary

    Viridans streptococci, including Streptococcus milleri, are increasingly recognized as pathogens in surgical patients. Prophylactic antibiotics may contribute to their emergence, necessitating long-term therapy for associated abscesses.

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    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Surgical Infections

    Background:

    • Viridans streptococci traditionally viewed as commensals, except in endocarditis.
    • Emerging evidence suggests Streptococcus milleri as a significant pathogen, causing severe sepsis.

    Purpose of the Study:

    • To review the clinical experience with Streptococcus milleri in general surgical patients.
    • To investigate potential factors contributing to the emergence of Streptococcus milleri as a pathogen.

    Main Methods:

    • Retrospective review of 23 general surgical patients over a 3-year period.
    • Analysis of cases involving Streptococcus milleri infections.

    Main Results:

    • Streptococcus milleri identified as a cause of life-threatening sepsis in surgical patients.
    • Postulation that prophylactic antibiotic combinations (e.g., gentamicin, metronidazole) in colorectal surgery may promote its emergence.

    Conclusions:

    • Streptococcus milleri is an emerging pathogen in surgical settings.
    • Long-term antibiotic therapy is recommended for established sepsis and abscesses caused by Streptococcus milleri.
    • Prophylactic antibiotic strategies in colorectal surgery warrant further investigation regarding their role in pathogen emergence.

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