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Related Experiment Videos

Dellen associated with filtering blebs.

H K Soong, H A Quigley

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |March 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Dellen, or corneal thinning, can occur after trabeculectomy surgery. Poor tear film integrity near the filtering bleb is the primary risk factor, though most cases resolve with minor treatment adjustments.

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    Area of Science:

    • Ophthalmology
    • Corneal Surgery
    • Glaucoma Surgery

    Background:

    • Trabeculectomy is a common surgical procedure for glaucoma.
    • Filtering blebs are a normal consequence of trabeculectomy.
    • Corneal dellen are localized thinning of the cornea.

    Observation:

    • Dellen formation was observed in 9 out of 97 consecutive trabeculectomies.
    • Most dellen cases healed without significant complications.
    • Two patients developed deep corneal ulcers secondary to dellen.

    Findings:

    • Poor tear-film integrity adjacent to the filtering bleb was the most significant predisposing factor for dellen.
    • Topical prednisolone acetate may inhibit corneal epithelial wound healing, potentially contributing to dellen.

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  • Aqueous tear secretion did not appear to significantly influence dellen formation.

    • Implications:

    • Identifying and managing tear-film abnormalities is crucial in preventing dellen after trabeculectomy.
    • Close monitoring of the cornea post-trabeculectomy is recommended, especially in patients with large filtering blebs.
    • Further research into the role of topical steroids in dellen pathogenesis may be warranted.