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Related Experiment Videos

Methylcellulose and lens implantation.

P U Fechner, M U Fechner

    The British Journal of Ophthalmology
    |April 1, 1983
    PubMed
    Summary

    Methylcellulose is a safe and effective agent for protecting the corneal endothelium during intraocular lens surgery. Its use in over 400 operations demonstrates its reliability and benefits in ophthalmic procedures.

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    Area of Science:

    • Ophthalmology
    • Biomaterials Science
    • Surgical Innovation

    Background:

    • Corneal endothelium damage is a risk during intraocular lens implantation.
    • Methylcellulose has been utilized since 1976 to mitigate this surgical risk.
    • Early methods involved a single drop, evolving to complete anterior chamber filling.

    Purpose of the Study:

    • To demonstrate the safety and efficacy of intraocular methylcellulose use.
    • To evaluate methylcellulose as a protective agent for the corneal endothelium.
    • To assess the feasibility of methylcellulose in complex intraocular surgeries.

    Main Methods:

    • Review of over 400 ophthalmic surgeries utilizing methylcellulose.
    • Application of methylcellulose solutions (1% and 2%) during intraocular lens implantation.
    • Observation of surgical outcomes and endothelial protection.

    Main Results:

    • Methylcellulose effectively maintained space between the cornea and iris, even with vitreous pressure.
    • No risk to the corneal endothelium was observed in the documented operations.
    • The substance proved safe for intraocular use across a significant patient cohort.

    Conclusions:

    • Intraocular methylcellulose is a safe and reliable agent for protecting the corneal endothelium.
    • Methylcellulose offers a cost-effective, readily available solution for ophthalmic surgery.
    • Its application facilitates complex intraocular procedures with reduced risk.

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