[Chromatin reorganization in a medium of physiological ionic strength in the presence of additional total histone]

The authors studied the capability of chromatin for structural reorganization in a medium of ionic strength, close to physiological one, under the effect of polyions of polycationic nature--summary histone of chromatin. Electrophoretic analysis demonstrated that like polyanions, summary histone forces out histone HI and partially histones H2B and H2A from chromatin. However, in contrast to polyanions, summary histone makes chromatin resistant to DNase-II, apparently potentiating the aggregation capability of chromatin despite the removal of histone HI.