Conjugate internalization of apposed plasma membranes in mouse olfactory bulb during postnatal development

Apposed plasma membranes of mitral cells and granule cell gemmules of mouse olfactory bulb are internalized in a conjugate fashion into mitral cell perikarya during postnatal development. Such conjugate internalization of plasma membranes occurs by way of double-walled coated vesicles (DWCVs) and becomes accelerated between 16 and 37 days of postnatal age. The formation of DWCVs appears to be a mechanism for the internalization of intercellularly adhered plasma membranes.