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Related Experiment Videos

Performance of the Hitachi 705 evaluated.

P Douville, J C Forest

    Clinical Chemistry
    |April 1, 1983
    PubMed
    Summary

    The Hitachi 705 discrete analyzer offers high throughput for 19 analytes. It demonstrated good reliability and practicability for most clinical chemistry assays, though calcium and phosphorus require further review.

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    Area of Science:

    • Clinical Chemistry
    • Analytical Instrumentation

    Background:

    • The Hitachi 705 is a new discrete analyzer designed for high-throughput clinical laboratory testing.
    • Evaluating new analytical instruments is crucial for ensuring reliable diagnostic capabilities.

    Purpose of the Study:

    • To assess the performance, reliability, and practicability of the Hitachi 705 discrete analyzer.
    • To evaluate the accuracy and precision of 11 common clinical chemistry assays performed on the instrument.

    Main Methods:

    • The Hitachi 705 analyzer was evaluated, focusing on its spectrophotometer, sample/reagent probes, and performance for 11 specific assays.
    • Precision (CV), linearity, and total analytical error were assessed for each assay.
    • Results were compared against medically allowable error limits.

    Main Results:

    • The instrument achieved a throughput of 180 tests per hour for up to 19 analytes.
    • Total imprecisions ranged from 0.14% to 8.0% across different components and assays.
    • Good linearity was observed for most tests, with acceptable analytical error, except for calcium and phosphorus.

    Conclusions:

    • The Hitachi 705 discrete analyzer demonstrates good reliability and practicability for a wide range of clinical chemistry assays.
    • While generally accurate, specific analytes like calcium and phosphorus may require further validation or method adjustment.

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