Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A device for rapid plasma separation.

J Umlas, G Gauvin, B Skane

    Critical Care Medicine
    |April 1, 1983
    PubMed
    Summary

    The STATSEP Plasma Separator offers rapid plasma separation by filtration, yielding results comparable to centrifugation for crucial blood analytes and coagulation tests. This filtration method saves significant time in laboratory diagnostics.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Canadian Surgery Forum: Abstracts of presentations to the Annual Meetings of the Canadian Association of Bariatric Physicians and Surgeons, Canadian Association of General Surgeons, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Association, Canadian Society of Surgical Oncology, Canadian Society of Colon and Rectal Surgeons, Vancouver, BC, Sept. 17-21, 2013.

    Canadian journal of surgery. Journal canadien de chirurgie·2025
    Same author

    Canadian Surgery Forum 2018: St. John's, NL Sept. 13-15, 2018.

    Canadian journal of surgery. Journal canadien de chirurgie·2022
    Same author

    Unusual presentations of malignancy. Case 1. Male inflammatory (?) breast cancer.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2001
    Same author

    Unusual sites of malignancy: case 2. Orbital lymphoma.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2001
    Same author

    Red coral keratitis.

    Cornea·2000
    Same author

    The cost-effectiveness of postoperative recovery of RBCs in preventing transfusion-associated virus transmission after joint arthroplasty.

    Transfusion·2000

    Area of Science:

    • Clinical Chemistry
    • Hematology
    • Medical Devices

    Background:

    • Conventional blood plasma separation relies on centrifugation, a time-consuming process.
    • Rapid and accurate plasma separation is critical for timely diagnostic testing.
    • The STATSEP Plasma Separator utilizes filtration technology for plasma generation.

    Purpose of the Study:

    • To evaluate the efficacy and accuracy of the STATSEP Plasma Separator compared to conventional centrifugation.
    • To assess the impact of filtration-based plasma separation on key blood analytes and coagulation parameters.
    • To determine the time efficiency of the STATSEP Plasma Separator in clinical laboratory settings.

    Main Methods:

    • Plasma was separated from whole blood using both the STATSEP Plasma Separator and conventional centrifugation.
    • Concentrations of various analytes were measured in duplicate specimens from both separation methods.
    • Prothrombin times (PT) and partial thromboplastin times (PTT) were measured on plasmas generated by both techniques.
    • Testing included patient samples with leukemia and varied platelet counts; elevated hematocrits were also considered.

    Main Results:

    • No clinically significant differences were observed in analyte concentrations between the two separation methods.
    • Prothrombin times (PT) and partial thromboplastin times (PTT) showed no significant variations.
    • The STATSEP Plasma Separator reduced the analytic time for coagulation tests by 9 minutes.
    • Plasma separation time was slightly increased with elevated hematocrits, requiring up to 2 minutes for 0.5 ml of plasma.

    Conclusions:

    • The STATSEP Plasma Separator provides a reliable and clinically equivalent alternative to centrifugation for plasma separation.
    • This filtration device significantly reduces turnaround time for critical coagulation tests.
    • The STATSEP Plasma Separator is cost-effective, easy to operate, and suitable for various patient populations, though high hematocrit may impact efficiency.

    Related Experiment Videos