Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Splanchnic circulation in hypertension.

R A Nyhof, G A Laine, G A Meininger

    Federation Proceedings
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evaluating the effects of immediate application of negative pressure therapy after decompression from abdominal compartment syndrome in an experimental porcine model.

    European journal of trauma and emergency surgery : official publication of the European Trauma Society·2016
    Same author

    Mesenteric lymphatic vessels adapt to mesenteric venous hypertension by becoming weaker pumps.

    American journal of physiology. Regulatory, integrative and comparative physiology·2014
    Same author

    Adaptation of mesenteric lymphatic vessels to prolonged changes in transmural pressure.

    American journal of physiology. Heart and circulatory physiology·2013
    Same author

    Decreased myosin phosphatase target subunit 1(MYPT1) phosphorylation via attenuated rho kinase and zipper-interacting kinase activities in edematous intestinal smooth muscle.

    Neurogastroenterology and motility·2012
    Same author

    Evaluation of gravimetric techniques to estimate the microvascular filtration coefficient.

    American journal of physiology. Regulatory, integrative and comparative physiology·2011
    Same author

    A murine model for the study of edema induced intestinal contractile dysfunction.

    Neurogastroenterology and motility·2010

    Arterial hypertension increases splanchnic vascular resistance and plasma protein leakage in humans. Animal models generally support these findings, indicating changes in arterioles and veins due to hypertension.

    Area of Science:

    • Physiology
    • Cardiovascular Research
    • Hypertension Studies

    Background:

    • Arterial hypertension significantly impacts systemic circulation.
    • The splanchnic circulation's response to hypertension requires detailed investigation.
    • Understanding these effects is crucial for managing hypertensive conditions.

    Purpose of the Study:

    • To assess the effects of arterial hypertension on splanchnic circulation.
    • To investigate changes in vascular resistance, permeability, and capacitance.
    • To compare findings in human essential hypertension with animal models.

    Main Methods:

    • Analysis of human essential hypertension data.
    • Review of various animal models of hypertension.
    • Examination of vascular resistance, transvascular escape rate, and venous capacitance.

    Related Experiment Videos

    Main Results:

    • In human hypertension, splanchnic vascular resistance increases proportionally with blood pressure.
    • Transvascular escape rate of plasma proteins is elevated in hypertensive humans.
    • Animal models generally mirror these changes, with evidence of arteriolar and venular alterations.

    Conclusions:

    • Hypertension alters splanchnic arteriolar responsiveness and permeability.
    • Degenerative histological changes and pressure-dependent mechanisms contribute to these alterations.
    • Reduced splanchnic venous capacitance suggests structural changes, necessitating further organ-specific research.