Intraocular blood flow from analysis of angiograms

A method of analysing fluorescein angiograms that yields a parameter of intraocular blood flow designated as the fluorescein appearance rate is presented. The appearance rate was decreased in those eyes in which intraocular pressure (Pi) was found to be increased. The appearance rate was also decreased in the two cases of "low tension glaucoma" whose angiograms we have analysed. The decrease in appearance rate with increase of Pi is the result of increasing vascular flow resistance due to constriction of veins at their exit from the eye.