Leiomyoma cutis and leiomyosarcoma: a 10-year study and a short review

Thirty-five cases of leiomyoma cutis (LMC) and 3 cases of leiomyosarcoma (LMS) were studied from the files of the Department of Pathology of the National Medical Center in El Salvador over a 10-year period. The LMC incidence was 0.04% and the LMS incidence was 0.003% (1 LMC for every 2,438.6 biopsies and 1 LMS for every 28,499.6 biopsies); 74.28% of the LMC occurred in females and 25.7% in males, with a ratio of 2.8 to 1. The average age was 32.1 in a range of 3 to 80 years. The higher frequency occurred in persons in their forties; 28.5% appeared on the upper limbs, 22.8% on the face, 20% on the thorax, 20% on the lower limbs, 2.8% in the perineal region, and 5.7% were of an unknown localization. In all cases, a solitary tumor was present. Microscopically, 88.5% corresponded to the pilar type, 8.5% were angioleiomyomas, and 3% were dartoic myomas. LMS occurred in 2 women and 1 man, affecting cheek, thigh, and back, and in 1 case, osseous metastasis occurred.