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Published on: February 9, 2011

Infection due to organisms of the Mycobacterium fortuitum complex after augmentation mammaplasty: clinical and

H W Clegg, M T Foster, W E Sanders

    The Journal of Infectious Diseases
    |March 1, 1983
    PubMed

    Insights

    Periprosthetic infections from Mycobacterium fortuitum and Mycobacterium chelonei are challenging after breast augmentation. These chronic, refractory wound infections often require delayed diagnosis and complicate further procedures.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Plastic Surgery

    Background:

    • Periprosthetic infections pose a significant challenge in reconstructive surgery.
    • Mycobacterium fortuitum and Mycobacterium chelonei are rapidly growing mycobacteria known to cause opportunistic infections.

    Purpose of the Study:

    • To describe the clinical characteristics and outcomes of periprosthetic infections caused by Mycobacterium fortuitum and Mycobacterium chelonei following breast augmentation.
    • To analyze the diagnostic challenges and treatment responses in these specific mycobacterial infections.

    Main Methods:

    • Retrospective case series analysis of 17 women with periprosthetic infections.
    • Review of clinical data, microbiological findings, and treatment regimens.
    • Antimicrobial susceptibility testing of Mycobacterium isolates.

    Main Results:

    • Seventeen cases of periprosthetic infection after breast augmentation were identified over 3.5 years.
    • Median incubation period was 28 days; diagnosis was often delayed.
    • Infections presented as chronic, refractory wounds with serosanguineous or purulent discharge.
    • Mycobacterium fortuitum isolates showed susceptibility to amikacin, but strain variability was noted.
    • Recurrent infections complicated revision surgeries.

    Conclusions:

    • Periprosthetic infections with rapidly growing mycobacteria are a serious complication of breast augmentation.
    • Early diagnosis and appropriate antimicrobial therapy are crucial but challenging.
    • These infections can lead to persistent morbidity and affect reconstructive outcomes.

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