Periodic acid-Schiff positive deposits associated with aging in mouse brains
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Updated: Oct 13, 2026

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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
Published on: March 23, 2011
Abstract:
Deposits which were heavily stained with periodic acid-Schiff's solution were observed in a serial study of mouse brain section. Their histochemical reactions to ferric acid, calcium, glycogen, amyloid, and mucopolysaccharide were negative. Many deposits were observed within 100 microns from the midline of the dorsal part of the ventral thalamic nucleus. The deposit sizes were directly related to the age of the mice (r2 = 0.99).

