[Pig skin xenograft in burns. I. Technology, laboratory studies. II. Clinical experience]

The technology of the preparation of certainly sterile xenograft--pig's skin has been examined by the authors before the therapeutical use. On the basis of their examinations it was found by the authors that 2500 krad gamma radiation is suitable for the sterilization of the pig's skin--for the preparation of both the nature or lyophilized skin--since at this radiation value the pig's skin suffers no injury. After the preparation of the xenograft its clinical use has been initiated with certainly sterile material in children with burns. Xenograft has been used on 50 occasions, chiefly after surgical necrectomy, as provisional biological dressing. On the basis of their satisfactors results the authors advocate the use of the xenograft in burns, in certain skin affections, in clinical pictures concomitant with skinning and cutaneous necrosis and generally in all cases, in which skin grafting in necessary.