Pathologic fetal heart rate associated with poor metabolic control in diabetic pregnancies

Nonstress fetal heart rate (FHR) recording was used as a primary test to detect fetal distress in 145 pregnant women with insulin-dependent diabetes. Testing was performed every second day beginning with the 32nd week of pregnancy and daily after the 34th week until delivery. One hundred eighteen (81.4%) had normal, nine (6.2%) suspicious, and 18 (12.4%) pathologic FHR recordings. Poor metabolic control of diabetes was observed in 25 (17.2%) of the 145 pregnancies during the last trimester of pregnancy. Nine of these 25 women (35%) with poor metabolic control had a suspicious or pathologic FHR recording, which was significantly more frequent (P less than .02) than in women with good metabolic control (18 of 120, 15%). The mean value (+/- SD) of hemoglobin AIc during the last trimester in diabetic women with pathologic FHR records was 7.63 +/- 0.87%, which was significantly higher (P less than .02) than in diabetic women with normal FHR records (6.91 +/- 0.83%). None of the 145 fetuses monitored died in utero. It was concluded that no obvious iatrogenic morbidity was caused by early intervention in cases with pathologic FHR recordings.