Cell marker studies in patients with newly diagnosed chronic lymphatic leukaemia

Cell marker analysis including mouse red cell rosetting ability was carried out on 24 newly diagnosed patients with chronic lymphatic leukaemia. Using a technique not employing neuraminidase a significant difference in mouse red cell rosetting ability was noted between male and female patients. It is well accepted that females often have a milder form of disease and better longterm survival than it is suggested this might be a reflection of the difference found in mouse red cell rosetting ability between the sexes in this condition.