[Chloramphenicol excretion in milk studied with a FAST (fully automated sample treatment) liquid chromatography...

The concentration of chloramphenicol (CAP) in milk following parenteral administration to cows was determined by FAST Liquid Chromatography. This method is 200 times more sensitive than microbiological procedures and may be used in examination on an extensive scale. The lowest detection limit is 0.05 ppm. Residues of CAP could be detected in the milk up to and including 32 hours after i.m. administration to three cows of a preparation containing 200 mg of CAP per ml.