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Contribution to the background of Mollaret's meningitis
Acta Neuropathologica
|January 1, 1983
Abstract:
An epidermoid cyst of the 3rd ventricle was verified by necropsy in a man of 60 with three episodes of Mollaret's aseptic leukocytic-endothelial meningitis. The authors accept the interpretation as macrophages of the "endothelial" cells. They bring forward evidence for the blastomatous nature of partly cornified epithelial cells present in their case. They suggest that cholesterin containing debris entering the subarachnoid space from the tumour cysts provoke an aseptic "chemical" meningitis of short course.
Insights
A rare 3rd ventricle epidermoid cyst was found in a man with recurrent aseptic meningitis. The cyst
Area of Science:
- Neuropathology
- Neuro-oncology
- Cerebrospinal Fluid Dynamics
Background:
- Epidermoid cysts are rare congenital tumors.
- Mollaret's meningitis is a recurrent aseptic meningitis.
Observation:
- A 60-year-old man presented with three episodes of Mollaret's meningitis.
- Necropsy revealed an epidermoid cyst of the 3rd ventricle.
Findings:
- The cyst contained partly cornified epithelial cells, suggesting blastomatous nature.
- Cholesterol crystals from the cyst likely induced aseptic chemical meningitis.
Implications:
- This case highlights a potential cause of recurrent aseptic meningitis.
- Understanding cyst-meningeal interactions is crucial for diagnosis and treatment.