Endoscopic evaluation and therapy of periampullary adenoma

Duodenoscopy has been helpful in the diagnosis and treatment of periampullary adenomas. Unlike colonic polyps, endoscopic appearance and histological classification is often difficult. A high incidence of carcinoma in these lesions requires their removal. Endoscopic polypectomy may be done, but only after documenting that the lesion does not contain ductal structures.