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Osteomyelitis caused by Veillonella
Abstract:
Veillonella parvula and alcalescens are anaerobic gram-negative cocci that, when isolated from anaerobic cultures of clinical specimens, are usually regarded as commensal organisms. Occasionally they play a pathogenic role and require antibiotic therapy. Limited clinical experience and in vitro susceptibility studies suggest that penicillin G is the drug of choice for these organisms and that cephalosporins, clindamycin, chloramphenicol, and metronidazole may be acceptable therapeutic alternatives. Presented herein is a case report of a Veillonella infection, a discussion of the importance of these organisms when they occur in a clinical infection, and a discussion of the appropriate antibiotic therapy.
Insights
Veillonella parvula and alcalescens are anaerobic bacteria, often commensal but sometimes pathogenic. Penicillin G is the preferred antibiotic, with alternatives like cephalosporins and clindamycin.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Bacteriology
Background:
- Veillonella parvula and Veillonella alcalescens are anaerobic, Gram-negative cocci.
- Typically considered commensal in clinical specimens.
- Can occasionally cause infections requiring antibiotic treatment.
Observation:
- A case of Veillonella infection is presented.
- Highlights the pathogenic potential of these normally commensal organisms.
- Discusses the clinical significance of Veillonella in infections.
Findings:
- Limited clinical data and in vitro studies guide antibiotic selection.
- Penicillin G is identified as the primary drug of choice.
- Cephalosporins, clindamycin, chloramphenicol, and metronidazole are potential alternatives.
Implications:
- Understanding Veillonella's role in infections is crucial for accurate diagnosis.
- Appropriate antibiotic therapy is essential for successful treatment outcomes.
- Further research may clarify the full spectrum of Veillonella pathogenicity and optimal management.