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Updated: Aug 6, 2026

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Insights
Clinical diagnosis of acute deep vein thrombosis (DVT) is unreliable. Noninvasive Doppler venous examinations offer 90% accuracy, reducing the need for costly venography in many patients.
Area of Science:
- Vascular Medicine
- Diagnostic Imaging
Background:
- Clinical diagnosis of acute deep vein thrombosis (DVT) has low accuracy (50%).
- Contrast venography is the gold standard but is expensive and invasive.
- Noninvasive tests are needed for accurate and accessible DVT diagnosis.
Purpose of the Study:
- To evaluate the accuracy and safety of using Doppler venous examinations as the primary diagnostic tool for suspected DVT.
- To assess the clinical utility of withholding contrast venography in patients with normal Doppler results.
Main Methods:
- A prospective study involving 186 patients with suspected DVT.
- All patients underwent a noninvasive Doppler venous examination.
- Contrast venography was withheld for patients with normal Doppler findings.
Main Results:
- Doppler venous examinations demonstrated high accuracy (approximately 90%) in diagnosing DVT.
- The study aimed to validate a practice of relying on Doppler results to guide further diagnostic and treatment decisions.
- This approach potentially reduces the number of contrast venograms performed.
Conclusions:
- A normal Doppler venous examination can reliably exclude DVT, obviating the need for contrast venography in many cases.
- This practice can decrease healthcare costs and patient discomfort associated with invasive procedures.
- Further evaluation confirmed the safety and validity of this diagnostic strategy.
Abstract:
The clinical diagnosis of acute deep vein thrombosis (DVT) is but 50% accurate when compared to the results of contrast venography. This clinical inaccuracy had led to the dependence of the physician upon laboratory diagnosis. Whereas contrast venography is the gold standard of diagnosis, its expense, special equipment, personnel, and discomfort make it unsuitable for evaluating large numbers of patients. For this reason, numerous noninvasive tests utilizing plethysmographic and Doppler techniques have been developed to evaluate patients with suspected venous disease, and when expertly performed have a degree of accuracy of approximately 90%. This degree of accuracy coincides with the experience of our peripheral vascular laboratory using the Doppler venous examination. Based on these statistics, our current practice is to evaluate patients suspected of having DVT with a Doppler venous examination (Figure 1). If the test is abnormal or equivocal, contrast venography is usually obtained and anticoagulation recommended. Contrariwise, if the Doppler venous examination is normal, venography is not obtained, and anticoagulation treatment is not recommended. This practice should reduce the number of venograms in a patient population that is not at an increased risk of pulmonary embolism or repeated deep venous thrombosis. To evaluate the validity and safety of this practice, one hundred eighty-six patients with normal Doppler venous examinations in whom contrast venography was not obtained were evaluated and form the basis of this report.
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