Polymorphism of the sixth component of complement (C6) in the dog

Isoelectric focusing was used to identify five alleles at the locus determining the production of the sixth component of complement (C6) in the dog. Four of these alleles, C6(1), C6(2), C6(4), and C6(5), were studied in family pedigrees and shown to be inherited in a codominant autosomal fashion. All alleles except for C6(4) occurred commonly in the multiple breeds tested.