Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abnormal evoked potential latencies in amblyopia.

S Sokol

    The British Journal of Ophthalmology
    |May 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Amblyopic children show altered visual evoked potential (VEP) wave latencies. Specifically, longer P1 and shorter P2 latencies in the amblyopic eye suggest a loss of contrast-specific mechanisms, impacting visual processing.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Signal to noise ratio considerations in the analysis of sweep visual-evoked potentials.

    Applied optics·2010
    Same author

    Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.

    Current biology : CB·2001
    Same author

    Myoglobin levels at 12 hours identify patients at low risk for 30-day mortality after thrombolysis in acute myocardial infarction: a Thrombolysis in Myocardial Infarction 10B substudy.

    American heart journal·2001
    Same author

    A role for Wnts in morpho-genesis and tissue polarity.

    Nature cell biology·2000
    Same author

    Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.

    Molecular and cellular biology·2000
    Same author

    Cngsc, a homologue of goosecoid, participates in the patterning of the head, and is expressed in the organizer region of Hydra.

    Development (Cambridge, England)·1999
    Same journal

    Reference map of multimodal vision deficits in intermediate age-related macular degeneration: contrast sensitivity and low-contrast visual acuity.

    The British journal of ophthalmology·2026
    Same journal

    Commentary on 'identifying patients with poor visual outcomes after primary rhegmatogenous retinal detachment surgery using machine learning'.

    The British journal of ophthalmology·2026
    Same journal

    Automated deep learning-based retinoschisis and detachment volume measurement in pathological myopia with posterior scleral contraction.

    The British journal of ophthalmology·2026
    Same journal

    Bacterial keratitis: a global review of current practices, challenges and innovations.

    The British journal of ophthalmology·2026
    Same journal

    Real-world integration of an autonomous artificial intelligence system for diabetic retinopathy screening in an endocrinology outpatient clinic.

    The British journal of ophthalmology·2026
    Same journal

    Maternal smoking during pregnancy: a risk factor for early childhood ophthalmologic conditions.

    The British journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Visual Science

    Background:

    • Amblyopia, or 'lazy eye,' affects visual development and acuity.
    • Visual evoked potential (VEP) measures the brain's electrical response to visual stimuli.
    • Understanding VEP changes in amblyopia can reveal underlying visual pathway deficits.

    Purpose of the Study:

    • To investigate pattern reversal visual evoked potential (VEP) latencies in children with amblyopia.
    • To compare VEP P1 and P2 wave latencies between amblyopic and normal eyes.
    • To explore the relationship between VEP findings and contrast processing in amblyopia.

    Main Methods:

    • Measured P1 and P2 wave latencies of VEPs in 68 normal and 32 amblyopic children.
    • Utilized small (15-minute arc) and large (60-minute arc) check sizes for VEP stimulation.

    Related Experiment Videos

  • Analyzed interocular latency differences in both groups.

    • Main Results:

    • Normal children exhibited no significant interocular P1 or P2 latency differences.
    • Amblyopic children displayed longer P1 latencies in their amblyopic eyes compared to fellow eyes.
    • Amblyopic eyes showed shorter P2 latencies for small checks, indicative of luminance response dominance.

    Conclusions:

    • Amblyopia may involve a selective deficit in contrast-specific VEP mechanisms.
    • Altered P2 latency in amblyopia reflects a shift towards luminance-based visual processing.
    • VEP analysis provides insights into the neural basis of visual impairment in amblyopia.