Methyclothiazide in hypertension. A report from the General Practitioner Research Group

In view of the statistically significant falls in blood pressure achieved at the end of two weeks only, it would seem that methyclothiazide is an effective antihypertensive agent, at least in the new cases of mild hypertension treated in this trial. The results are, perhaps, particularly impressive in view of the fact that the majority of patients were treated with the smaller dose of 5mg daily. In this trial, postural hypotension was of no importance whatsoever, and the incidence of side effects was minimal. Methyclothiazide would seem to be a suitable choice for the treatment of mild hypertension in general practice.