Carcinogenic metabolites of 5-methylchrysene

Synthesis is described of trans-1,2-dihydroxy-1,2-dihydro-5-methylchrysene and trans-1,2-dihydroxy-anti-3,4-epoxy-1,2,3,4-tetrahydro-5-methylchrysene, implicated as the proximate and ultimate carcinogenic metabolites, respectively, of the potent environmental carcinogen 5-methylchrysene.