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Right ventricular function in Chagas disease.

H A Carrasco, M Medina, G Inglessis

    International Journal of Cardiology
    |January 1, 1983
    PubMed
    Summary
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    Chagas disease affects the heart diffusely, impacting the left ventricle earlier and more severely than the right. This study recommends cineventriculograms for evaluating right ventricular function before pacemaker implantation in chagasic patients.

    Area of Science:

    • Cardiology
    • Infectious Diseases
    • Medical Imaging

    Background:

    • Chagas disease, caused by *Trypanosoma cruzi*, is a significant cause of cardiomyopathy.
    • Right ventricular function is crucial for overall cardiac health, but its assessment in Chagas disease can be challenging.

    Purpose of the Study:

    • To investigate the impact of Chagas disease on right ventricular function.
    • To correlate electrocardiogram (ECG) findings and left ventricular damage with right ventricular abnormalities.
    • To determine the utility of cineventriculography in assessing ventricular function in Chagasic patients.

    Main Methods:

    • Cardiac catheterization and cineventriculography (right and left) were performed in 60 chagasic patients and 15 controls.
    • Patients were categorized based on ECG findings and left ventricular damage severity.

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  • Right ventricular function, dilatation, and segmental wall motion abnormalities were assessed.

    • Main Results:

    • Chagasic patients with normal ECGs and left ventricles had normal right ventricular function.
    • Early left ventricular damage was associated with right ventricular dilatation and/or asynergy.
    • Advanced left ventricular damage and congestive heart failure correlated with marked right ventricular dilatation, depressed contractility, and apical motion abnormalities.

    Conclusions:

    • Chagas disease is a diffuse cardiomyopathy affecting both ventricles, with earlier and more pronounced left ventricular involvement.
    • Segmental abnormalities are common in the apical and para-apical regions of both ventricles.
    • Cineventriculography of both right and left ventricles is recommended prior to cardiac pacemaker implantation in chagasic individuals.