[Anaphylaxis following ingestion of coffee, chronic urticaria and analgesics idiosyncrasy]

In a 45-year-old woman with chronic urticaria anaphylactoid reactions occurred after (1) ingestion of coffee and (2) taking an analgesic drug. Prick testing in the patient and passive cutaneous anaphylaxis with coffee extract in the monkey Macacus nemestrinus were positive. With regard to further prick tests and oral provocation tests there is conclusive evidence that anaphylactic hypersensitivity to coffee was co-existing with idiosyncrasy to acetylsalicylic acid, indomethacne, metamizole (dipyrone), and caffeine.