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Characteristics of normal and refluxing ureterovesical junctions
The Journal of Urology
|April 1, 1983
Summary
Vesicoureteral reflux is linked to lower ureteral peristaltic frequency and a failure to maintain pressure gradients at the ureterovesical junction (UVJ) during bladder filling.
Area of Science:
- Urology
- Physiology
Background:
- Vesicoureteral reflux (VUR) is a common condition in children.
- Understanding the ureterovesical junction (UVJ) mechanism is crucial for diagnosing and managing VUR.
Purpose of the Study:
- To quantitatively define the mechanism of ureterovesical junction (UVJ) competence.
- To investigate the physiological differences between competent and refluxing UVJs.
Main Methods:
- Ureteral pressures were measured using a continuously perfused catheter with a single side opening.
- Studies were conducted under general anesthesia on 11 competent and 9 refluxing UVJs.
Main Results:
- Ureteral contraction amplitude was similar in both groups.
- Peristaltic frequency was significantly lower in refluxing UVJs.
- Refluxing UVJs showed a decreased ability to maintain a pressure gradient with bladder filling.
Conclusions:
- Refluxing ureters exhibit reduced peristaltic frequency.
- Impaired pressure gradient maintenance at the UVJ contributes to vesicoureteral reflux.