Effects of bradykinin on renal lymph flow and composition

It has been reported that bradykinin causes permeability changes with increased vascular leakage in many peripheral tissues, but not in the renal parenchyma. In the present experiments, the effects of bradykinin on renal hilar lymph flow and concentrations of protein and PAH were studied. The results of these experiments show that the protein permeability of the intrarenal vessels from which lymph is derived is not altered by bradykinin. The data presented does, however, suggest that renal lymph may contain tubular reabsorbate, a component from the glomerulus, or both. In addition, data is presented which suggests that a significant amount of lymph may be formed in the renal medulla during renal vasodilation.