Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Unexplained spastic paraplegia.

I D Wallace, J E Cosnett

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |April 30, 1983
    PubMed
    Summary
    This summary is machine-generated.

    In a study of Black patients with paraplegia, 33 cases had unexplained causes, suggesting a potential toxic dietary factor. Further research is needed to identify the specific dietary elements responsible for this neurological condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Charles Dickens and the neurological consequences of alcoholism.

    Addiction (Abingdon, England)·2000
    Same author

    Charles Dickens and epilepsy.

    Epilepsia·1994
    Same author

    Dickens and doctors: vignettes of Victorian medicine.

    BMJ (Clinical research ed.)·1992
    Same author

    Charles Dickens: observer of sleep and its disorders.

    Sleep·1992
    Same author

    Dickens, dystonia and dyskinesia.

    Journal of neurology, neurosurgery, and psychiatry·1991
    Same author

    Therapeutics in retrospect: iron carbonate in chorea and tic douloureux.

    Journal of the Royal Society of Medicine·1990

    Area of Science:

    • Neurology
    • Tropical Medicine
    • Dietary Science

    Background:

    • Paraplegia presents a significant neurological challenge, particularly in certain populations.
    • Previous reports from South Africa and tropical regions have noted similar unexplained cases.

    Purpose of the Study:

    • To investigate the characteristics and potential causes of unexplained paraplegia in Black patients.
    • To explore the association between dietary factors and corticospinal tract degeneration.

    Main Methods:

    • Retrospective analysis of 330 Black patients admitted with paraplegia.
    • Clinical evaluation focusing on neurological deficits, including corticospinal tract and sensory pathways.
    • Exclusion of known causes of paraplegia through comprehensive investigation.

    Related Experiment Videos

    Main Results:

    • 33 out of 330 patients (10%) had paraplegia with unexplained etiology.
    • These patients exhibited predominant corticospinal tract degeneration and milder sensory loss.
    • The clinical presentation aligns with previously described cases from tropical regions.

    Conclusions:

    • A toxic dietary factor is the most probable cause for this specific group of unexplained paraplegia cases.
    • Further etiological investigation into dietary habits in affected populations is warranted.
    • This highlights a potential public health concern in tropical and subtropical areas.