Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

IgE suppression by maternal IgG.

E E Jarrett, E Hall

    Immunology
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Maternal milk transfers antibodies to offspring, suppressing their IgE antibody production while enhancing IgG responses. This maternal immune transfer may prevent infantile allergies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inducing emesis in Australian dogs and cats: agents, adverse effects and antiemetic administration.

    Australian veterinary journal·2025
    Same author

    Investigations into disease associations with feline immunodeficiency virus (FIV) infection in lions (Panthera leo) in Australia: a case-control study.

    Australian veterinary journal·2024
    Same author

    Antiviral therapy in cats progressively infected with feline leukaemia virus: lessons from a series of 18 consecutive cases from Australia.

    Australian veterinary journal·2024
    Same author

    A survey investigating owner perceptions and management of firework-associated fear in dogs in the Greater Sydney area.

    Australian veterinary journal·2024
    Same author

    Diagnosis and surgical management of an extraskeletal osteosarcoma of the brachial plexus in a Belgian shepherd dog.

    The Journal of small animal practice·2024
    Same author

    Ophthalmic findings associated with Australian tick paralysis (holocyclotoxicity) in hospitalized domestic dogs and cats.

    Veterinary ophthalmology·2024
    Same journal

    Epidermal Dominance of Metabolically Constrained Immune Niches Underpins Immune Activation Signatures and Clinical Severity in Psoriatic Disease.

    Immunology·2026
    Same journal

    Thymic APC Networks Orchestrate T-Cell Selection: Mechanisms and Therapeutic Opportunities in Immune Disorders.

    Immunology·2026
    Same journal

    Immune Checkpoints in Leukaemia as Gatekeepers of Immuno-Modulation.

    Immunology·2026
    Same journal

    Senescent Human Liver Endothelial Cells Mediate CD4<sup>+</sup> T Cell Recruitment via ICOSL.

    Immunology·2026
    Same journal

    The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ<sup>+</sup>CD4<sup>-</sup>CD8<sup>-</sup> Double Negative T Cells in lpr Lupus Mice.

    Immunology·2026
    Same journal

    Epigenetic Gene Networks Governing Immune State Transitions Across the Lifespan.

    Immunology·2026
    See all related articles

    Area of Science:

    • Immunology
    • Developmental Biology

    Background:

    • Maternal factors transferred via milk influence offspring immune development.
    • Egg albumin-specific IgE antibody production is diminished in offspring of immunized rats.

    Purpose of the Study:

    • To investigate the mechanism of maternal immune transfer on offspring antibody production.
    • To determine the role of maternal IgG in suppressing IgE responses in offspring.

    Main Methods:

    • Administration of immune serum to neonatal rats.
    • Measurement of egg albumin-specific IgE and IgG antibody levels in offspring.
    • Analysis of antibody transfer via maternal milk.

    Main Results:

    • Maternal milk transfers egg albumin-specific IgG to suckling rats.

    Related Experiment Videos

  • Offspring exhibit suppressed IgE and enhanced IgG responses to egg albumin.
  • Maternal IgG levels in offspring decline post-weaning, but immune effects persist.

    • Conclusions:

    • Maternal IgG transferred via milk suppresses offspring IgE antibody production.
    • This suppression may be a physiological mechanism to prevent infantile allergies.
    • Circulating antibody blocking is unlikely to be the sole mechanism of suppression.