Related Experiment Video
Updated: Aug 13, 2026

Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models
Published on: April 7, 2018
Sonographic findings of pancreatitis in children
Insights
Sonography effectively detects pediatric pancreatitis by analyzing pancreatic size and echogenicity. A specific P/V ratio combined with hypoechoic parenchyma strongly indicates acute pancreatitis in children.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Imaging
- Pancreatic Diseases
Background:
- Pancreatitis in children presents diagnostic challenges.
- Elevated amylase levels are a key indicator but require confirmation.
- Imaging modalities are crucial for accurate diagnosis.
Purpose of the Study:
- To evaluate the utility of sonography in diagnosing pancreatitis in children.
- To correlate pancreatic size and echogenicity with amylase levels.
- To establish sonographic criteria for identifying acute pancreatitis.
Main Methods:
- Retrospective analysis of sonographic findings in children.
- Measurement of pancreatic dimensions and echogenicity.
- Correlation of sonographic data with serum amylase levels.
- Calculation of the pancreas-to-vertebral body (P/V) ratio.
Main Results:
- A P/V ratio > 0.3 with hypoechoic pancreatic parenchyma indicated acute pancreatitis.
- The predictive value of a positive sonogram was 0.93.
- The predictive value of a negative sonogram was 0.78.
- Sonography demonstrated high accuracy in detecting pediatric pancreatitis.
Conclusions:
- Sonography is a valuable tool for diagnosing pancreatitis in children.
- It serves as an effective adjunct to amylase level determination.
- Specific sonographic features can reliably identify acute pancreatitis.
Abstract:
The size and echogenicity of the pancreas was evaluated with real-time and static sonography and correlated in an independent and retrospective manner with amylase values in 17 asymptomatic children, 19 children with acute pancreatitis, and 2 with chronic pancreatitis. A ratio of the greatest anteroposterior dimension of the body of the pancreas relative to the transverse lumbar vertebral body measurement (P/V ratio) greater than 0.3, when associated with a hypoechoic pancreatic parenchyma, was indicative of acute pancreatitis. The predictive value of a positive sonogram was found to be 0.93, whereas the predictive value of a negative sonogram was 0.78. These data indicate that sonography is a useful adjunct to amylase determinations in the detection of pancreatitis in children.
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology

