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Plasma copper and zinc concentrations and infertility
British Journal of Obstetrics and Gynaecology
|May 1, 1983
Summary
Low plasma copper levels were observed in infertile women compared to fertile controls, suggesting a potential link between copper deficiency and female infertility. Zinc levels showed no significant difference between groups.
Area of Science:
- Biochemistry
- Reproductive Biology
- Human Physiology
Background:
- Female infertility is a significant global health concern.
- Trace elements play crucial roles in various physiological processes, including reproduction.
- Copper and zinc are essential minerals with known roles in cellular function.
Purpose of the Study:
- To investigate the association between plasma copper and zinc concentrations and female infertility.
- To compare trace element levels in infertile women versus fertile controls.
Main Methods:
- Plasma samples were collected from 48 infertile women and 35 control subjects.
- Plasma copper and zinc concentrations were measured.
- Statistical analysis was performed to compare groups.
Main Results:
- Plasma copper concentration was significantly lower in infertile women compared to control subjects.
- Women with secondary infertility had slightly lower plasma copper than those with primary infertility.
- Plasma zinc concentration did not differ significantly between infertile and fertile women.
Conclusions:
- Low plasma copper concentration may be a contributing factor to female infertility.
- Further research is warranted to elucidate the precise role of copper in human female fertility.