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Hypoglycemia associated with pediatric surgical procedures.

S Mercer, J Bass

    Canadian Journal of Surgery. Journal Canadien De Chirurgie
    |May 1, 1983
    PubMed
    Summary
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    Perioperative hypoglycemia, or low blood glucose, occurred in infants undergoing surgery, particularly those with necrotizing enterocolitis complications. Inadequate caloric intake was a key factor, increasing mortality risk and potential for infant brain damage.

    Area of Science:

    • Pediatric Surgery
    • Neonatal Medicine
    • Metabolic Disorders

    Background:

    • Hypoglycemia, defined as plasma glucose below 2.2 mmol/l, is a critical concern in infants.
    • Neonatal necrotizing enterocolitis is a serious condition in newborns that can lead to surgical complications.
    • Perioperative care in infants requires careful metabolic monitoring.

    Purpose of the Study:

    • To investigate the incidence and associations of perioperative hypoglycemia in infants.
    • To identify risk factors and outcomes related to hypoglycemia in this population.
    • To highlight the potential for neurological complications.

    Main Methods:

    • Retrospective analysis of 61 operative procedures in 46 infants.
    • Identification of perioperative hypoglycemia events (plasma glucose < 2.2 mmol/l).

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  • Correlation of hypoglycemia with patient demographics, surgical complications, caloric intake, and mortality.
  • Main Results:

    • Hypoglycemia was observed 8 times perioperatively.
    • The condition was most prevalent in infants with neonatal necrotizing enterocolitis complications.
    • Inadequate perioperative caloric intake was strongly associated with hypoglycemia and increased mortality.

    Conclusions:

    • Perioperative hypoglycemia in infants is linked to significant morbidity and mortality.
    • Neonatal necrotizing enterocolitis complications are a key risk factor.
    • The high glucose demands of the infant brain necessitate vigilant management to prevent cerebral damage.