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Related Experiment Videos

Marjolin's ulcer. The LSU experience.

L H Barr, J W Menard

    Cancer
    |July 1, 1983
    PubMed
    Summary

    Marjolin's ulcers, skin cancers from chronic wounds, show aggressive behavior. Prophylactic lymph node dissection is likely unnecessary for most patients, as local treatments are often effective.

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    Area of Science:

    • Oncology
    • Dermatology
    • Surgical Pathology

    Background:

    • Marjolin's ulcers, skin cancers arising in chronic injury sites, are often aggressive.
    • Management of regional lymph nodes in these cases is controversial.

    Observation:

    • This study reviewed 37 patients with Marjolin's ulcers treated with local surgical modalities (wide excision or amputation).
    • Recurrence rates and metastatic disease were evaluated based on treatment type.

    Findings:

    • Amputation: 3/18 recurred, with metastatic disease.
    • Wide excision: 5/16 recurred (2 metastatic, 3 cured with further surgery).
    • Overall, only 17.6% developed regional node metastases, suggesting local recurrences are manageable.

    Implications:

    • Prophylactic lymph node dissection may not be required for most Marjolin's ulcer patients.
    • Local surgical treatments like wide excision or amputation can be effective.
    • Recurrences are often local and amenable to further surgical intervention.

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