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Primary calcification in remodeling haversian systems following tibial fracture in rats
Clinical Orthopaedics and Related Research
|June 1, 1983
Abstract:
Electron micrographs of fracture callus obtained ten days after injury show typical primary matrix vesicle mineralization. In remodeling haversian canals distant from the fracture sites, matrix vesicles and calcifying nodules were observed. The occurrence of these elements was also found to control unfractured tibiae with intramedullary nails but not normal bone. These observations suggest that during haversian remodeling, mineralization after osseous or marrow tissue damage is associated with matrix vesicles.
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Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...

