[Effect of hyperbaric oxygenation on the microsomal enzymes of the liver monooxygenase system in the rat]

Hyperbaric oxygenation of rats made at a pressure of 303.9 kPa (3 at. abs.) and 3-hour exposure induces in liver microsomes an increase (for 12 h) followed by a drop of NADP X H-ferricytochrome-c-reductase activity, reversible fall of cytochrome P-450 content, and inhibition of the rates of amidopyrine N-demethylation and aniline p-hydroxylation. Activity of NADP X H-nitrotetrasolium-, NAD X H-ferricyanide-, NAD X H-cytochrome-c-reductase and the content of cytochrome b5 remains essentially unchanged.