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Abstract:
A case of primary papillary mesothelioma of the ovary is reported and its microscopic and ultrastructural features described. This tumour was an incidental surgical finding and was accompanied by multiple, partially cystic, peritoneal lesions with similar microscopic features. The histological pattern was predominantly papillary with well-differentiated mesothelial cells and a prominent stromal infiltrate that included large numbers of lymphocytes and lipid-filled macrophages. A comparison is made with adenomatoid tumours and with other tumours of ovarian epithelium and it is suggested that this tumour may represent the benign counterpart of one form of clear cell carcinoma of the ovary. The presence of multiple peritoneal lesions may indicate limited malignant potential comparable to some other papillary epithelial neoplasms of the ovary.
Insights
A rare primary papillary mesothelioma of the ovary was found incidentally. Multiple peritoneal lesions suggest potential limited malignant behavior.
Area of Science:
- Gynecologic pathology
- Mesothelial proliferations
- Ovarian neoplasms
Background:
- Primary papillary mesothelioma of the ovary is a rare neoplasm.
- Understanding its features is crucial for differential diagnosis.
Observation:
- A case presented as an incidental surgical finding.
- Multiple, partially cystic peritoneal lesions with similar microscopic features were present.
- Histology showed a predominantly papillary pattern with well-differentiated mesothelial cells.
Findings:
- Stromal infiltrate included lymphocytes and lipid-filled macrophages.
- Microscopic features were compared to adenomatoid tumours and ovarian epithelial tumours.
- The tumour may be the benign counterpart of ovarian clear cell carcinoma.
Implications:
- Multiple peritoneal lesions may indicate limited malignant potential.
- Further research is needed to fully characterize this rare ovarian tumour.
- This finding contributes to the spectrum of ovarian epithelial neoplasms.