Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Regional lung function in erect humans after lobectomy.

J A Fleetham, H Clarke, N R Anthonisen

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The pain funding gap: A database analysis of pain research funding in Canada from 2008-2023.

    Canadian journal of pain = Revue canadienne de la douleur·2025
    Same author

    Letter of Response Regarding Adrenal SABR to the Article Published in the March 2024 Journal Publication: Prospective Longitudinal Assessment of Quality of Life after Stereotactic Ablative Radiotherapy for Oligometastases: Analysis of the Population-based SABR-5 Phase II Trial by Cruz-Lim et al.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2024
    Same author

    Observations of Rogue Seas in the Southern Ocean.

    Physical review letters·2024
    Same author

    Association of peri-operative prescription of non-steroidal anti-inflammatory drugs with continued prescription of opioids after total knee arthroplasty: a retrospective claims-based cohort study.

    Anaesthesia·2024
    Same author

    Cdk12 maintains the integrity of adult axons by suppressing actin remodeling.

    Cell death discovery·2023
    Same author

    The evolving culture of medical cannabis in Canada for the management of chronic pain.

    Frontiers in pharmacology·2023

    Lung lobectomy causes remaining lung areas to overexpand, altering regional lung volumes and gas exchange. This study reveals how lung weight and chest wall shape influence these changes after surgery.

    Area of Science:

    • Pulmonary physiology
    • Thoracic surgery outcomes
    • Medical imaging and diagnostics

    Background:

    • Lobectomy is a common surgical procedure for lung diseases.
    • Understanding post-lobectomy lung mechanics is crucial for patient recovery.
    • Previous studies have not fully elucidated regional volume distribution changes.

    Purpose of the Study:

    • To investigate regional lung volume distribution and gas washout in patients after lobectomy.
    • To compare operated lungs with contralateral, unoperated lungs.
    • To identify factors influencing lung expansion and ventilation post-surgery.

    Main Methods:

    • Utilized the 133Xe (Xenon-133) technique for regional lung function assessment.
    • Studied adult subjects post-lobectomy, comparing operated and unoperated lung sides.

    Related Experiment Videos

  • Analyzed lung volumes, washout half times, and regional gradients at various lung volumes.

    • Main Results:

    • Lobectomy resulted in increased lung expansion and prolonged washout times compared to control lungs.
    • Apex-to-base volume gradients were normal in upper lobectomy but reduced in lower lobectomy cases.
    • Relative overexpansion of basal regions was observed in lower lobectomy patients.

    Conclusions:

    • Post-lobectomy lung expansion is influenced by factors beyond increased functional residual capacity.
    • Lung weight and lung-chest wall shape interactions significantly determine regional lung volume distribution.
    • Findings suggest compensatory overexpansion in remaining lung segments, particularly in basal regions after lower lobectomy.